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Results: We identified three novel homozygous loss-of-function mutations (c.2927_2928delCT, p.(Pro976Argfs*42)

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International journal of nephrology and renovascular disease

Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling

This mechanism is largely route-independent at the cellular level, which is why it is invoked for both topical and injectable use but a shared mechanism does not by itself prove that either route produces a visible skin outcome